Model CYP3A4 induction mediated drug-drug interaction (rifampicin and alprazolam        < Prev | Next >
Google+ login   Facebook login   Register  
Module name  
Module name  
PHML Model Management

CYP3A4 induction mediated drug-drug interaction (rifampicin and alprazolam

Simulation Result

Model Properties

Model Revision2
DBID796
Registration2014-06-29 10:12:13
Last Update2014-06-29 10:12:13
Root ModuleIntestinalLumen
Number of Modules22
Description Rifampicin is a strong inducer of cytochrome P450 3A4 (CYP3A4). When coadministered with rifampicin, clearance of alprazolam, a typical CYP3A4 substrate, is enhanced.

Creator Information

NameFumiyoshi Yamashita
OrganizationKyoto University, Graduate School of Pharmaceutical Sciences
Emailyama@pharm.kyoto-u.ac.jp

IDPHPL NAMELAST UPDATE
Clear    0
PQ_NAMETYPEPHPLORIGINAL

Creator Information

Name
Organization
  Modify Current Model   Update Model   Delete This Model
Graphs of Simulation Results
  • Add

  • If you are sure that the following information is already described in the model, you can leave them empty now.
    Creator information
    Name:
    Organization:
    Email:
    PHML Model
      Private   Public
    Graphs of Simulation Results
    Figure:
    Variable:
    Time step:
    Length
    Method:
    Simulator:
  • Add


  • If you are sure that the following information is already described in the model, you can leave them empty now.
    Creator information
    Name:
    Organization:
    Email:
  • Add
  • Delete this model.  If there are several revisions, only this revision of the model is deleted from the database.